Body Mist vs. Perfume: The Biggest Difference The primary difference is fragrance concentration. Perfumes generally contain a higher concentration of fragrance materials, which creates a stronger scent and longer wear time. Body mists typically contain less fragrance and are designed to create a softer, more refreshing fragrance experience. That difference changes how you wear them. Perfume is usually applied sparingly to pulse points. Body mist can be applied more generously